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큐Do you want to take a guess at how many of those "sure winners" end up passing clinical trials? Seven percent. That's 7% of the best drugs that emerged from the best science and were so promising that a pharma company invested $10 million to more than $1 billion to test the drugs in patients. Ninety-three percent of the "winners" fail.⇉

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◩The high-profile case, which pits an artist's freedom to riff on existing works of art against the protection of an artist from copyright infringement, hinges on whether Warhol's images of Prince transform Goldsmith's photograph to a great enough degree to stave off claims of copyright infringement and therefore be considered as "fair use." Under copyright law, fair use permits the unlicensed appropriation of copyright-protected works in specific circumstances, for example, in some non-commercial or educational cases.◧0819R-74H⇦That kind of capaciousness is also a notable stylistic quality of the novel. At times, we might wonder why almost every character has a backstory or why certain subplots exist. Ever the skillful surgeon, Verghese threads meaningful connections between macrocosmic and microcosmic details so elegantly that they are often barely noticeable at first. For example, the parallel narratives of the Parambil family, the Scottish doctor Digby Kilgour, and the Swedish doctor Rune Orquist seem like they could each be entire novels on their own. Instead, Verghese takes his time to reveal how everything, like the waterways there, is connected and eventually flows together.▶CGA3E2X7R2A223K080AE✄Following a 3-1 victory over a team called Boreham Wood on Saturday, Wrexham has gained promotion — the process by which a club moves into a higher quality playing tier — and starting in August will take its place in League Two, which is actually the fourth highest tier in English soccer.♤VS-60APU04LHN3⇊Woods "made the cut" — meaning he played well enough in the first two rounds of the tournament to move on to the second half — for the 23rd consecutive time, tying the record for the most made cuts of all time with Fred Couples and Gary Player.✉

▧As a once metalhead myself (my subgenres of choice: thrash, glam, and power metal), I found a great deal to enjoy in John Wray's sixth novel, Gone to the Wolves, which masterfully portrays the heavy metal scene of the late 1980s and early 1990s through the eyes of Floridian teenagers. But don't let the topic scare you off; like any good novel about a subculture (or several), Wray's newest does not require prior knowledge of or interest in metal in order to enjoy it.ΘC324C621F3G5TA☠Gabino Iglesias is an author, book reviewer and professor living in Austin, Texas. Find him on Twitter at @Gabino_Iglesias.☀

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VJ1210V685MXARW1BC♚King Charles III's coronation Saturday will have a shorter parade route, a role for all Britons rather than only aristocrats — and a nod to the country's myriad faiths.✿0603J0160100JCR◘That includes bans on gender-affirming medical care for minors, restrictions on the types of restrooms transgender people can use, measures restricting classroom instruction on sexual orientation and gender identity, and bills that would out transgender students who want teachers to address them by the pronouns they use.☆

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J110⇣Delphin Birimbi, a civic leader in Kalehe, said he understood that thousands of people remained missing. He told the AP that some doctors arrived to treat the injured but communities were pleading for more emergency assistance.✡RPER71H473K2P1A03B↢“Once the emergencies are over with, you don’t really know what happens in those individual lives afterwards,” Sikes said. “You do have to kind of reset and be prepared for the next emergency.”♡

☁"Policy differences between the parties should not stop Congress from avoiding default," Biden said after the meeting, adding the leaders will "speak regularly over the next several days" as staff continues to meet daily.◦